Good's Buffers

Achieve stable, reproducible results in your experiments with Good’s buffers, a trusted choice for biological and biochemical research. Originally developed by Norman E. Good in the 1960s, these zwitterionic compounds are designed to maintain precise pH control in aqueous solutions, particularly under physiological conditions. Explore our range of Good's buffers for:

  • Minimal biomolecular interaction ensures accuracy in sensitive assays
  • High chemical stability prevents degradation and variability
  • Low experimental interference maintains the integrity of cell culture, enzyme assays, and protein purification workflows

Whether you're optimizing experimental conditions or scaling up research, our Good’s buffers help you achieve reproducibility and precision every time.

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Frequently Asked Questions

Good’s buffers are a set of zwitterionic compounds designed to maintain stable pH in biochemical and biological research. They are widely used in cell culture, enzyme assays, and protein purification due to their high stability and minimal reactivity with biomolecules.

Common Good’s buffers include HEPES, MES, MOPS, PIPES, Tris, and Tricine. Each buffer is designed for specific pH ranges and applications, ensuring optimal performance in biological and biochemical experiments.

The selection depends on the required pH range and application. For example, HEPES is ideal for physiological conditions, MES is used in protein purification, and Tricine is optimal for SDS-PAGE separation of low molecular weight proteins.