RNA lysis buffer is formulated to rapidly disrupt cells and tissues while protecting RNA from degradation. Its combination of chaotropic agents and detergents ensures complete inactivation of RNases, delivering high-integrity RNA for sensitive downstream applications.
Effectively lyses cells while inactivating RNases to preserve RNA integrity
Yields high-quality RNA for RT-PCR, RNA-seq, and transcriptomics workflows
Compatible with manual and automated RNA isolation protocols
Whether you're isolating total RNA from cultured cells, tissues, or blood samples, our RNA lysis buffer provides the stability and purity your molecular analyses demand.
Read More
Frequently Asked Questions
What are the key components of RNA lysis buffer?
It typically contains chaotropic agents like guanidinium thiocyanate, detergents to disrupt membranes, and stabilizers to protect RNA integrity during extraction.
Can this buffer be used with all cell types and tissues?
Yes, it is suitable for a wide range of sample types including cultured cells, tissue biopsies, and blood, though some fibrous tissues may require mechanical disruption.
Is RNA lysis buffer compatible with downstream RNA purification kits?
Yes, it works with silica column-based kits, magnetic bead systems, and organic extraction protocols such as phenol-chloroform.
