Red blood cell (RBC) lysis buffer is formulated to selectively remove erythrocytes from whole blood or tissue samples while preserving nucleated cells and biomolecules for downstream analysis. This enables cleaner sample preparation with minimal impact on white blood cells, DNA, RNA, or proteins.
Efficiently removes red blood cells while leaving other cell types intact
Preserves leukocytes and nucleic acids for accurate downstream results
Prepared samples for applications like flow cytometry, and DNA, RNA, and protein extractions
Whether you're processing samples for immune profiling, molecular diagnostics, or cell-based assays, our RBC lysis buffer simplifies your workflow and protects what matters most.
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Frequently Asked Questions
How does RBC lysis buffer work?
It uses a hypotonic or chemically selective solution to disrupt red blood cells without damaging leukocytes or other target components.
Is this buffer compatible with downstream molecular applications?
Absolutely. Properly formulated RBC lysis buffers preserve DNA, RNA, and proteins, making them suitable for qPCR, RNA-seq, or proteomics workflows.
How long does it take to lyse red blood cells?
Most protocols take 5-10 minutes at room temperature, depending on sample volume and buffer strength.
